課程資訊
課程名稱
藥物傳輸系統
Drug Delivery Systems 
開課學期
100-1 
授課對象
工學院  醫學工程學研究所  
授課教師
黃義侑 
課號
Biomed7014 
課程識別碼
548 M0300 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
 
備註
本課程中文授課,使用英文教科書。教室:基醫505
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1001ta_DDS 
課程簡介影片
 
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課程概述

一、課程簡介:
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems. Lectures include:
1. Concepts and System Design forthe Rate-Controlled Drug Delivery
2. Mathematical Modeling of Controlled Drug Delivery
3. Oral Drug Delivery and Delivery System
4. Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic
Administration (Rectal & Oral musosa DDS)
5. Nasal/ Pulmonary Drug Delivery and Delivery System
6. Transdermal Drug Delivery and Delivery System
7. Ocular Drug Delivery and Delivery System
8. Polymers for Drug delivery, EVA, Silicone...
and Natural Biodegradable Polymer in Drug Delivery System
9. Synthetic Biodegradable Polymer in Drug Delivery System
10. Compartmental Models and Their Application
11. Drug Targeting
12. Liposome Drug Delivery
13. Study Report

二、先修課程:無

三、參考書目:
1. H. C. Ansel and N. G. Popovich “Pharmaceutical Dosage Forms and drug Delivery System” Lea & Febiger Philadelphia, 6th Ed 1995
2. Y.W. Chien `Novel Drug Delivery Systems` 1992 Marcel Dekker Inc,
3. C.G. Wilson and N. Washington “ Physiological Pharmaceutics : Biological Barriers to Drug Absorption” 1989 Ellis Horwood Limited
4. 橋田 充 “生體內藥物送達學”

 

課程目標
Introduction to the application of engineering principles and biological considerations in designing drug delivery system for medical uses.
The concept of biocompatibility and its implications in formulating controlled release devices will be illustrated.emphasis will be given to the use of biodegradable materials to design drug delivery systems for site-specific application. the concepts of mathematical modeling of controlled release drug delivery systems will be covered. 
課程要求
無 
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
無 
參考書目
無 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
期末報告 
25% 
上台報告及書面報告 
2. 
期中考 
27% 
 
3. 
平時考/上課成績 
20% 
 
4. 
期末考 
28% 
 
 
課程進度
週次
日期
單元主題
第1週
9/15  drug delivery:the basic concept 
第2週
9/22  drug delivery:market perspectives 
第3週
9/29  adavanced durg delivery and targeting :an introduction I 
第4週
10/06  adavanced durg delivery and targeting :an introduction II 
第5週
10/13  rate control in drug delivery and targeting:fundamentals and applications to implantable systems I 
第6週
10/20  rate control in drug delivery and targeting:fundamentals and applications to implantable systems II 
第7週
10/27  drug targeting system:fundamentals and applications to parenteral durg delivery I 
第8週
11/03  drug targeting system:fundamentals and applications to parenteral durg delivery II 
第9週
11/10  期中考 
第10週
11/17  oral durg delivery 
第11週
11/24  oral trans-mucosal durg delivery 
第12週
12/01  transdermal durg delivery 
第13週
12/08  nasal durg delivery
 
第14週
12/15  Study Report 
第15週
12/22  Liposome Drug Delivery  
第16週
12/29  Study Report 
第17週
1/05  Study Report